Concepedia

Piribedil disrupts the MLL1-WDR5 interaction and sensitizes MLL-rearranged acute myeloid leukemia (AML) to doxorubicin-induced apoptosis

Xiong Zhang, Xingling Zheng, Hong Yang, Juan Yan, Xuhong Fu, Rongrui Wei, Xiaowei Xu, Zhuqing Zhang, Aisong Yu, Kaixin Zhou,

Cancer Letters · 2018 · 29 citations · 33 references

DOI

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33

Genetic abnormalities in myelodysplasia and secondary acute myeloid leukemia: impact on outcome of stem cell transplantation

Tetsuichi Yoshizato, Yasuhito Nannya, Yoshiko Atsuta et al. · Blood · 2017 · 352 citations · Full text

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Targeting MLL1 H3K4 Methyltransferase Activity in Mixed-Lineage Leukemia

Fang Cao, Elizabeth C. Townsend, Hacer Karataş et al. · Molecular Cell · 2014 · 302 citations · Full text

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Global chromatin profiling reveals NSD2 mutations in pediatric acute lymphoblastic leukemia

Jacob D. Jaffe, Yan Wang, Ho Man Chan et al. · Nature Genetics · 2013 · 284 citations · Full text

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Structural basis for activity regulation of MLL family methyltransferases

Yanjing Li, Jianming Han, Yuebin Zhang et al. · Nature · 2016 · 253 citations · Full text

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Multiple Interactions Recruit MLL1 and MLL1 Fusion Proteins to the HOXA9 Locus in Leukemogenesis

Thomas A. Milne, Jaehoon Kim, Gang Greg Wang et al. · Molecular Cell · 2010 · 228 citations · Full text

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