Juan Yan

CTC clusters induced by heparanase enhance breast cancer metastasis

Rongrui Wei, Danni Sun, Hong Yang et al. · Acta Pharmacologica Sinica · 2018 · 105 citations

Medicine, Cancer Biology, Oncology +14

Design, Synthesis, and Biological Evaluation of the First c-Met/HDAC Inhibitors Based on Pyridazinone Derivatives

Dong Lu, Juan Yan, Lang Wang et al. · ACS Medicinal Chemistry Letters · 2017 · 46 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +13

Aspirin disrupts the mTOR-Raptor complex and potentiates the anti-cancer activities of sorafenib via mTORC1 inhibition

Danni Sun, Hong‐Chun Liu, Xiaoyang Dai et al. · Cancer Letters · 2017 · 39 citations

Medicine, Oncology, Pharmacology +14

CUDC-907 displays potent antitumor activity against human pancreatic adenocarcinoma in vitro and in vivo through inhibition of HDAC6 to downregulate c-Myc expression

Xuhong Fu, Xiong Zhang, Hong Yang et al. · Acta Pharmacologica Sinica · 2018 · 38 citations · Full text

Medicine, Medicinal Chemistry, Oncology +12

Piribedil disrupts the MLL1-WDR5 interaction and sensitizes MLL-rearranged acute myeloid leukemia (AML) to doxorubicin-induced apoptosis

Xiong Zhang, Xingling Zheng, Hong Yang et al. · Cancer Letters · 2018 · 29 citations

Medicine, Oncology, Pharmacology +14