Assessment of the effects of levosimendan and thymoquinone on lung injury after myocardial ischemia reperfusion in rats

Abstract

The findings in our study have shown that administration of levosimendan and TQ during I/R increases expression of caspase 3, p53, and Bax in lung tissue and has a protective effect on lung as distant organ. We suggest that findings of this study be elucidated with further large-scale clinical studies.