Concepedia

A “top-down” approach to actuate poly(amine-co-ester) terpolymers for potent and safe mRNA delivery

Yuhang Jiang, Alice Gaudin, Junwei Zhang, Tushar Agarwal, Eric Song, Amy C. Kauffman, Gregory T. Tietjen, Yongheng Wang, Zhaozhong Jiang, Christopher J. Cheng,

Biomaterials · 2018 · 73 citations · 31 references

DOI

Concepts

References

31

Cationic liposome-mediated RNA transfection.

Robert W. Malone, Philip L. Felgner, Inder M. Verma · Proceedings of the National Academy of Sciences · 1989 · 893 citations · Full text

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A Single Administration of CRISPR/Cas9 Lipid Nanoparticles Achieves Robust and Persistent In Vivo Genome Editing

Jonathan D. Finn, Amy Smith, Mihir Patel et al. · Cell Reports · 2018 · 847 citations · Full text

, , +17

Optimization of Lipid Nanoparticle Formulations for mRNA Delivery in Vivo with Fractional Factorial and Definitive Screening Designs

Kevin Kauffman, J. Robert Dorkin, Jung Hoon Yang et al. · Nano Letters · 2015 · 768 citations

, , +17

Expression of therapeutic proteins after delivery of chemically modified mRNA in mice

Michael Kormann, Günther Hasenpusch, Manish K. Aneja et al. · Nature Biotechnology · 2011 · 739 citations

, , +12

Vector unpacking as a potential barrier for receptor-mediated polyplex gene delivery

David V. Schaffer, Nick A. Fidelman, Nily Dan et al. · Biotechnology and Bioengineering · 2000 · 521 citations

, , +17