Christopher J. Cheng

MicroRNA silencing for cancer therapy targeted to the tumour microenvironment

Christopher J. Cheng, Raman Bahal, Imran Babar et al. · Nature · 2014 · 832 citations · Full text

Cancer Therapy, Tumor Biology, Biological Microenvironments +10

In vivo CRISPR base editing of PCSK9 durably lowers cholesterol in primates

Kiran Musunuru, Alexandra C. Chadwick, Taiji Mizoguchi et al. · Nature · 2021 · 713 citations

Knockout Mouse, Genetics, Genetic Engineering +8

Nanoparticle-based therapy in an in vivo microRNA-155 (miR-155)-dependent mouse model of lymphoma

Imran Babar, Christopher J. Cheng, Carmen J. Booth et al. · Proceedings of the National Academy of Sciences · 2012 · 486 citations

Biodegradable poly(amine-co-ester) terpolymers for targeted gene delivery

Jiangbing Zhou, Jie Liu, Christopher J. Cheng et al. · Nature Materials · 2011 · 386 citations · Full text

Engineering, Polymer Science, Targeted Gene Delivery +3

In vivo correction of anaemia in β-thalassemic mice by γPNA-mediated gene editing with nanoparticle delivery

Raman Bahal, Nicole McNeer, Elias Quijano et al. · Nature Communications · 2016 · 180 citations · Full text