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Design, synthesis and biological evaluation of N-phenyl-(2,4-dihydroxypyrimidine-5-sulfonamido)benzoyl hydrazide derivatives as thymidylate synthase (TS) inhibitors and as potential antitumor drugs

Medicinal ChemistryDerivative (Chemistry)Bioorganic ChemistryMedicineNatural SciencesPotential Antitumor DrugsThymidylate SynthasePharmacotherapyAnti-cancer AgentDrug DevelopmentPharmacologyPharmaceutical ChemistryBiomolecular EngineeringDrug DiscoveryBenzoyl Hydrazide Derivatives