Concepedia

The discovery and preclinical evaluation of BMS-707035, a potent HIV-1 integrase strand transfer inhibitor

B. Narasimhulu Naidu, Michael Walker, Margaret E. Sorenson, Yasutsugu Ueda, John D. Matiskella, Timothy P. Connolly, Ira B. Dicker, Zeyu Lin, Sagarika Bollini, Brian Terry,

Bioorganic & Medicinal Chemistry Letters · 2018 · 15 citations · 10 references

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10

Discovery of Raltegravir, a Potent, Selective Orally Bioavailable HIV-Integrase Inhibitor for the Treatment of HIV-AIDS Infection

Vincenzo Summa, Alessia Petrocchi, Fabio Bonelli et al. · Journal of Medicinal Chemistry · 2008 · 634 citations · Full text

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The developability of heteroaromatic and heteroaliphatic rings – do some have a better pedigree as potential drug molecules than others?

Timothy J. Ritchie, Simon J. F. Macdonald, Simon Peace et al. · MedChemComm · 2012 · 178 citations

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The Molecular Biology of HIV Integrase

Robert Craigie · Future Virology · 2012 · 74 citations · Full text

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Design of Novel Bioisosteres of β-Diketo Acid Inhibitors of HIV-1 Integrase

Mario Sechi, Luciano Sannia, Fabrizio Carta et al. · Antiviral chemistry & chemotherapy · 2005 · 59 citations · Full text

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Synthesis and evaluation of C2-carbon-linked heterocyclic-5-hydroxy-6-oxo-dihydropyrimidine-4-carboxamides as HIV-1 integrase inhibitors

B. Narasimhulu Naidu, Margaret E. Sorenson, Manoj Patel et al. · Bioorganic & Medicinal Chemistry Letters · 2014 · 48 citations · Full text

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