Concepedia

CAR T cell–induced cytokine release syndrome is mediated by macrophages and abated by IL-1 blockade

Theodoros Giavridis, Sjoukje J. C. van der Stegen, Justin Eyquem, Mohamad Hamieh, Alessandra Piersigilli, Michel Sadelain

Nature Medicine · 2018 · 1.3K citations · 27 references

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27

Chimeric Antigen Receptor T Cells for Sustained Remissions in Leukemia

Shannon L. Maude, Noelle V. Frey, Pamela A. Shaw et al. · New England Journal of Medicine · 2014 · 5.4K citations · Full text

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T cells expressing CD19 chimeric antigen receptors for acute lymphoblastic leukaemia in children and young adults: a phase 1 dose-escalation trial

Daniel W Lee, James N. Kochenderfer, Maryalice Stetler‐Stevenson et al. · The Lancet · 2014 · 2.9K citations

, , +17

Long-Term Follow-up of CD19 CAR Therapy in Acute Lymphoblastic Leukemia

Jae H. Park, Isabelle Rivière, Mithat Gönen et al. · New England Journal of Medicine · 2018 · 2.7K citations · Full text

, , +17

Efficacy and Toxicity Management of 19-28z CAR T Cell Therapy in B Cell Acute Lymphoblastic Leukemia

Marco L. Davila, Isabelle Rivière, Xiuyan Wang et al. · Science Translational Medicine · 2014 · 2.5K citations · Full text

, , +17

Endothelial Activation and Blood–Brain Barrier Disruption in Neurotoxicity after Adoptive Immunotherapy with CD19 CAR-T Cells

Juliane Gust, Kevin A. Hay, Laïla‐Aïcha Hanafi et al. · Cancer Discovery · 2017 · 1.4K citations · Full text

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