The exercise-inducible bile acid receptor Tgr5 improves skeletal muscle function in mice

Takashi Sasaki, Ayane Kuboyama, Moeko Mita, Shotaro Murata, Makoto Shimizu, Jun Inoue, Kazutoshi Mori, Ryuichiro Sato

Journal of Biological Chemistry · 2018 · 100 citations · 39 references

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Abstract

α KO mice, indicating that Atf6α is essential for this response. These findings indicate that the bile acid receptor Tgr5 contributes to improved muscle function and provide an additional explanation for the beneficial effects of exercise on skeletal muscle activity.

References

39