Concepedia

Targeting the RhoA-ROCK pathway to regulate T-cell homeostasis in hypoxia-induced pulmonary arterial hypertension

Cheng Li, Pingping Liu, Doudou Tang, Yiqing Zhang, Si Lei, Shangjie Wu

Pulmonary Pharmacology & Therapeutics · 2018 · 37 citations · 38 references

DOI

Concepts

References

38

Hypoxia Inducible Factor 1 Mediates Hypoxia-Induced TRPC Expression and Elevated Intracellular Ca <sup>2+</sup> in Pulmonary Arterial Smooth Muscle Cells

Jian Wang, Letitia Weigand, Wenju Lu et al. · Circulation Research · 2006 · 341 citations · Full text

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Regulatory T Cells Limit Vascular Endothelial Injury and Prevent Pulmonary Hypertension

Rasa Tamošiūnienė, Wen Tian, Gundeep Dhillon et al. · Circulation Research · 2011 · 309 citations

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Selective oral ROCK2 inhibitor down-regulates IL-21 and IL-17 secretion in human T cells via STAT3-dependent mechanism

Alexandra Zanin‐Zhorov, Jonathan M. Weiss, Melanie Nyuydzefe et al. · Proceedings of the National Academy of Sciences · 2014 · 253 citations · Full text

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Lung tissues in patients with systemic sclerosis have gene expression patterns unique to pulmonary fibrosis and pulmonary hypertension

Eileen Hsu, Haiwen Shi, Rick Jordan et al. · Arthritis & Rheumatism · 2010 · 233 citations · Full text

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Lysophosphatidic Acid Induces Neointima Formation Through PPARγ Activation

Chunxiang Zhang, Daniel L. Baker, Satoshi Yasuda et al. · The Journal of Experimental Medicine · 2004 · 201 citations · Full text

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