Publication | Closed Access
Synthesis of novel 1,2,3-triazole based artemisinin derivatives and their antiproliferative activity
48
Citations
36
References
2018
Year
Medicinal ChemistryDerivative (Chemistry)Antiproliferative ActivityMedicineDrug DiscoveryApoptosisCell DeathArtemisinin DerivativesCell CycleAnti-cancer AgentG2/m PhasePharmacologyCell BiologyPharmaceutical ChemistryNovel Artemisinin-1,2,3-triazole DerivativesBiomolecular EngineeringNatural Product Synthesis
Novel artemisinin-1,2,3-triazole derivatives show significant antiproliferative activity, and induce apoptosis and ROS generation and arrest the cell cycle at the G2/M phase.
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