Real-time monitoring of the aggregation of Alzheimer's amyloid-β <i>via</i><sup>1</sup>H magic angle spinning NMR spectroscopy

Jian Wang, Tomoya Yamamoto, Jia Bai, Sarah J. Cox, Kyle J. Korshavn, Martine Monette, Ayyalusamy Ramamoorthy

Chemical Communications · 2018 · 31 citations · 23 references

Concepts

Abstract

monomers increases the rate of formation of aggregates, and that the increasing lag-time with peptide concentration suggests the formation of growth-incompetent species. EGCG's ability to shift off-pathway aggregation is also demonstrated.

References

23