Molecular Pharmacology · 2017 · 113 citations · 40 references
MedicineMedicinal ChemistryPharmacologyMolecular PharmacologyPharmacodynamicsSignal TransductionAllosteric ModulationLigand BindingOpioid AnalgesicsOpioid PharmacologyReceptor PharmacologyReceptor-ligand InteractionsAllosteric Modulation Of G Protein-coupled ReceptorsAllosteric Modulation Of ReceptorsLigand Binding AffinityPositive Allosteric ModulationPositive Allosteric ModulatorsReceptor Allosteric SitesReceptorsSelectivity
40
Crystal structure of the µ-opioid receptor bound to a morphinan antagonist
Aashish Manglik, Andrew C. Kruse, Tong Sun Kobilka et al. · Nature · 2012 · 1.4K citations
Structural Basis for Allosteric Regulation of GPCRs by Sodium Ions
Wei Liu, Eugene Chun, Aaron A. Thompson et al. · Science · 2012 · 965 citations · Full text
Structural insights into µ-opioid receptor activation
Weijiao Huang, Aashish Manglik, AJ Venkatakrishnan et al. · Nature · 2015 · 911 citations · Full text
Structure of the human κ-opioid receptor in complex with JDTic
Huixian Wu, Daniel Wacker, Mauro Mileni et al. · Nature · 2012 · 871 citations · Full text
Molecular cloning and functional expression of a mu opioid receptor from rat brain
Yan Chen, Anton Mestek, Jian Liu et al. · Regulatory Peptides · 1994 · 810 citations