Concepedia

Inhibiting mitochondrial phosphate transport as an unexploited antifungal strategy

Catherine A. McLellan, Benjamin Vincent, Norma V. Solis, Alex K. Lancaster, Lucas B. Sullivan, Cathy L Hartland, Willmen Youngsaye, Scott G. Filler, Luke Whitesell, Susan Lindquist

Nature Chemical Biology · 2017 · 51 citations · 28 references

DOIFull text

Open access

Concepts

References

28

New Substructure Filters for Removal of Pan Assay Interference Compounds (PAINS) from Screening Libraries and for Their Exclusion in Bioassays

Jonathan B. Baell, Georgina A. Holloway · Journal of Medicinal Chemistry · 2010 · 3.9K citations

, , +14

Development of a Second-Generation Antiandrogen for Treatment of Advanced Prostate Cancer

Chris Tran, Samedy Ouk, Nicola J. Clegg et al. · Science · 2009 · 2.3K citations · Full text

, , +17

An Essential Role of the Mitochondrial Electron Transport Chain in Cell Proliferation Is to Enable Aspartate Synthesis

Kıvanç Birsoy, Walter W. Chen, Elizaveta Freinkman et al. · Cell · 2015 · 1.4K citations · Full text

, , +12

Hsp90 Potentiates the Rapid Evolution of New Traits: Drug Resistance in Diverse Fungi

Leah E. Cowen, Susan Lindquist · Science · 2005 · 704 citations

, , +17

Systematic screens of a Candida albicans homozygous deletion library decouple morphogenetic switching and pathogenicity

Suzanne M. Noble, Sarah French, Lisa A. Kohn et al. · Nature Genetics · 2010 · 688 citations · Full text

, , +12