Leah E. Cowen

Hsp90 Potentiates the Rapid Evolution of New Traits: Drug Resistance in Diverse Fungi

Leah E. Cowen, Susan Lindquist · Science · 2005 · 700 citations

Engineering, Fungal Cell Biology, Genetics +19

Harnessing Hsp90 function as a powerful, broadly effective therapeutic strategy for fungal infectious disease

Leah E. Cowen, Sheena D. Singh-Babak, Julia R. Köhler et al. · Proceedings of the National Academy of Sciences · 2009 · 407 citations · Full text

Fungal Cell Biology, Immunology, Clinical Mycology +16

Hsp90 Governs Echinocandin Resistance in the Pathogenic Yeast Candida albicans via Calcineurin

Sheena D. Singh-Babak, Nicole Robbins, Aimee K. Zaas et al. · PLoS Pathogens · 2009 · 355 citations · Full text

Antifungal Agent, Fungal Cell Biology, Antifungal Agents +15

PKC Signaling Regulates Drug Resistance of the Fungal Pathogen Candida albicans via Circuitry Comprised of Mkc1, Calcineurin, and Hsp90

Shantelle L. LaFayette, Cathy Collins, Aimee K. Zaas et al. · PLoS Pathogens · 2010 · 330 citations · Full text

Fungal Pathogens, Antifungal Agent, Signal Transduction +15

Acquisition of Aneuploidy Provides Increased Fitness during the Evolution of Antifungal Drug Resistance

Anna Selmecki, Keely Dulmage, Leah E. Cowen et al. · PLoS Genetics · 2009 · 328 citations · Full text

Biology, Drug Resistance Analysis, Antifungal Agent +15