Escherichia coli as a model organism for systems metabolic engineering

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Jeffrey D. Orth, Ines Thiele, Bernhard Ø. Palsson · Nature Biotechnology · 2010 · 4.1K citations

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Quantitative prediction of cellular metabolism with constraint-based models: the COBRA Toolbox v2.0

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Life Sciences, Bioinformatics, Systems Biology +17

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Life Sciences, Bioinformatics, Genetics +11

Analysis of optimality in natural and perturbed metabolic networks

Daniel Segrè, Dennis Vitkup, George M. Church · Proceedings of the National Academy of Sciences · 2002 · 1.4K citations

Life Sciences, Biochemistry, Biology +15