Concepedia

Direct interaction of menin leads to ubiquitin-proteasomal degradation of β-catenin

Byungho Kim, Tae-Yang Song, Kwan Young Jung, Seul Gi Kim, Eun‐Jung Cho

Biochemical and Biophysical Research Communications · 2017 · 13 citations · 18 references

DOI

Concepts

References

18

Menin Associates with a Trithorax Family Histone Methyltransferase Complex and with the Hoxc8 Locus

Christina M. Hughes, Orit Rozenblatt–Rosen, Thomas A. Milne et al. · Molecular Cell · 2004 · 635 citations · Full text

, , +15

Menin Interacts with the AP1 Transcription Factor JunD and Represses JunD-Activated Transcription

Sunita Agarwal, Siradanahalli C. Guru, Christina Heppner et al. · Cell · 1999 · 622 citations · Full text

, , +5

Menin, the product of the <i>MEN1</i> gene, is a nuclear protein

Siradanahalli C. Guru, Paul K. Goldsmith, A. Lee Burns et al. · Proceedings of the National Academy of Sciences · 1998 · 429 citations · Full text

, , +13

Wnt signaling regulates pancreatic β cell proliferation

Ingrid C. Rulifson, Satyajit Karnik, Patrick W. Heiser et al. · Proceedings of the National Academy of Sciences · 2007 · 341 citations · Full text

, , +15

The same pocket in menin binds both MLL and JUND but has opposite effects on transcription

Jing Huang, Buddha Gurung, Bingbing Wan et al. · Nature · 2012 · 307 citations · Full text

, , +4