A critical role for elastin signaling in vascular morphogenesis and disease

Satyajit Karnik, Benjamin S. Brooke, Antoni Bayés‐Genís, +5

Development

Menin regulates pancreatic islet growth by promoting histone methylation and expression of genes encoding p27 <i> ^Kip1 </i> and p18 <i> ^INK4c </i>

Satyajit Karnik, Christina M. Hughes, Xueying Gu, +5

Proceedings of the National Academy of Sciences

Histone ModificationsEpigenetic ChangeCancer BiologyEpigeneticsInsulin Signaling +21

Menin Controls Growth of Pancreatic ß-Cells in Pregnant Mice and Promotes Gestational Diabetes Mellitus

Satyajit Karnik, Hainan Chen, Graeme W. McLean, +6

Science

Developmental BiologySignal TransductionMenin Controls GrowthEndocrine MechanismMedicine +13

Wnt signaling regulates pancreatic β cell proliferation

Ingrid C. Rulifson, Satyajit Karnik, Patrick W. Heiser, +7

Proceedings of the National Academy of Sciences

Beta Cell ProliferationInsulin SignalingMolecular PhysiologySignal TransductionTissue Development +13

The axonal attractant Netrin-1 is an angiogenic factor

Kye Won Park, Dana Crouse, Mark Lee, +5

Proceedings of the National Academy of Sciences

MechanobiologyBlood VesselsParallel TrajectoriesAngiogenesisDevelopmental Biology +12

Heterogeneous gene expression signatures correspond to distinct lung pathologies and biomarkers of disease severity in idiopathic pulmonary fibrosis

Daryle J. DePianto, Sanjay Chandriani, Alexander R. Abbas, +14

Thorax

Elastin induces myofibrillogenesis via a specific domain, VGVAPG

Satyajit Karnik, Joshua D. Wythe, Lise K. Sorensen, +3

Matrix Biology

MechanobiologyCardiomyopathySignal TransductionPhysiologySpecific Domain +6

Goblet cell-specific expression mediated by the<i>MUC2</i>mucin gene promoter in the intestine of transgenic mice

James R. Gum, James W. Hicks, Anne-Marie Gillespie, +6

American Journal of Physiology-Gastrointestinal and Liver Physiology

Reduction of Liver Steatosis and Fibrosis with an Ask1 Inhibitor in a Murine Model of Nash is Accompanied by Improvements in Cholesterol, Bile Acid and Lipid Metabolism

Grant R. Budas, Satyajit Karnik, T. Jonnson, +4

Journal of Hepatology

Metabolic SyndromeHepatologyMedicineLiver PhysiologyMurine Model +10

Menin-mediated Caspase 8 Expression in Suppressing Multiple Endocrine Neoplasia Type 1

Ping La, Yuqing Yang, Satyajit Karnik, +4

Journal of Biological Chemistry

Tumor BiologyEndocrine OncologySignaling PathwayCell RegulationCaspase 8 +13