Dietary Genistein Influences Number of Acetylcholine Receptors in Female Diabetic Jejunum

Abstract

These data suggest that slowed intestinal transit in the diabetic <i>ob/ob</i> mouse may be due in part to decreased AChR and decreased contraction events occurring per unit time. A genistein diet rescues the number of AChR to levels of leans yet did not change the number of contractile events. Feeding <i>ob/ob</i> mice a genistein-rich diet has potential therapeutic benefits towards improving the debilitating diabetes-related gastrointestinal dysfunction.