Concepedia

Acyclonucleosides bearing coplanar arylethynyltriazole nucleobases: synthesis, structural analysis, and biological evaluation

Mimi Chen, Zhengwei Zhou, Yaxiong Suo, Mengyao Li, Jianhua Yao, Ling Peng, Yi Xia

New Journal of Chemistry · 2017 · 12 citations · 19 references

DOI

Concepts

Abstract

The efficient synthesis of acyclonucleosides bearing coplanar 3-arylethynyltriazole motifs was established and several compounds displayed antiproliferative activity against cancer cells.

References

19

Palladium‐Catalyzed Cross‐Coupling: A Historical Contextual Perspective to the 2010 Nobel Prize

Carin C. C. Johansson Seechurn, Matthew O. Kitching, Thomas J. Colacot et al. · Angewandte Chemie International Edition · 2012 · 3K citations · Full text

, , +12

The broad-spectrum antiviral ribonucleoside ribavirin is an RNA virus mutagen

Shane Crotty, David Maag, Jamie J. Arnold et al. · Nature Medicine · 2000 · 818 citations

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Stochastic exploration of molecular mechanics energy surfaces. Hunting for the global minimum

Martin Saunders · Journal of the American Chemical Society · 1987 · 302 citations

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Copper Catalysis for Selective Heterocoupling of Terminal Alkynes

Lebin Su, Jianyu Dong, Long Liu et al. · Journal of the American Chemical Society · 2016 · 152 citations

, , +11

Novel Triazole Ribonucleoside Down-Regulates Heat Shock Protein 27 and Induces Potent Anticancer Activity on Drug-Resistant Pancreatic Cancer

Yi Xia, Yang Liu, Jinqiao Wan et al. · Journal of Medicinal Chemistry · 2009 · 96 citations

, , +15