Concepedia

Nucleobase Synthesis

Nucleobase Synthesis is a chemical methodology that constitutes the de novo construction of nitrogen-containing heterocyclic compounds known as nucleobases, which serve as the fundamental building blocks of nucleic acids, through controlled organic reactions that selectively form the characteristic purine or pyrimidine ring systems.

1.1K

Publications

38.5K

Citations

3.2K

Authors

733

Institutions

Publications per year

2017–2026

72

Parents

Publications

1.1K

LNA (Locked Nucleic Acids): Synthesis of the adenine, cytosine, guanine, 5-methylcytosine, thymine and uracil bicyclonucleoside monomers, oligomerisation, and unprecedented nucleic acid recognition

Alexei A. Koshkin, Sanjay K. Singh, Poul Nielsen et al. · Tetrahedron · 1998 · 1K citations

, , +16

Nucleoside syntheses, XXII<sup>1)</sup> Nucleoside synthesis with trimethylsilyl triflate and perchlorate as catalysts

Helmut Vorbrüggen, Konrad Krolikiewicz, Bärbel Bennua · Chemische Berichte · 1981 · 755 citations

, , +14

Synthesis of 2′-O,4′-C-methyleneuridine and -cytidine. Novel bicyclic nucleosides having a fixed C3, -endo sugar puckering

Satoshi Obika, Daishu Nanbu, Yoshiyuki Hari et al. · Tetrahedron Letters · 1997 · 601 citations

, , +13

Nucleosides and Nucleotides

Kazunobu Miura, Masatoshi SHIGA, Tohru Ueda · The Journal of Biochemistry · 1973 · 487 citations

, , +15

Synthesis of carbocyclic nucleosides

Luigi A. Agrofoglio, Edouard Suhas, Audrey Farèse et al. · Tetrahedron · 1994 · 379 citations

, , +12

1–5 of 1.1K

Authors

3.2K

  1. MJ
    Morris J. Robins

    Brigham Young University, United States

    24 publications · 1.3K citations

    19

    h-index

  2. JJ
    Jack J. Fox

    Kettering University, United States

    16 publications · 915 citations

    14

    h-index

  3. AM
    Akira Matsuda

    Hokkaido University, Japan

    20 publications · 586 citations

    14

    h-index

  4. RP
    Radek Pohl

    Czech Academy of Sciences, Institute of Organic Chemistry and Biochemistry, Czechia

    16 publications · 530 citations

    13

    h-index

  5. MH
    Michal Hocek

    Czech Academy of Sciences, Institute of Organic Chemistry and Biochemistry, Czechia

    16 publications · 505 citations

    13

    h-index

1–5 of 3.2K

Institutions

733

  1. Centre National de la Recherche Scientifique

    Paris, France

    19 h-index

    126 publications

    3.7K citations

  2. Czech Academy of Sciences, Institute of Organic Chemistry and Biochemistry

    Prague, Czechia

    18 h-index

    111 publications

    4.2K citations

  3. Hokkaido University

    Sapporo, Japan

    16 h-index

    83 publications

    2.7K citations

  4. The University of Tokyo

    Tokyo, Japan

    14 h-index

    52 publications

    1.4K citations

  5. Rega Institute for Medical Research

    Leuven, Belgium

    14 h-index

    64 publications

    2.7K citations

  6. Kettering University

    Flint, United States

    13 h-index

    48 publications

    1.6K citations

  7. Nagoya University

    Nagoya, Japan

    13 h-index

    60 publications

    1.9K citations

  8. KU Leuven

    Leuven, Belgium

    13 h-index

    64 publications

    2.7K citations

1–8 of 733

Venues

  1. The Journal of Organic Chemistry

    JOC · 110 publications · 4.4K citations

    37

    h-index

  2. Tetrahedron Letters

    122 publications · 3.8K citations

    30

    h-index

  3. Journal of the American Chemical Society

    JACS · 30 publications · 2.5K citations

    26

    h-index

  4. Tetrahedron

    55 publications · 2.8K citations

    24

    h-index

  5. Organic Letters

    OL · 39 publications · 1.2K citations

    22

    h-index

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