Concepedia

LNA (Locked Nucleic Acids): Synthesis of the adenine, cytosine, guanine, 5-methylcytosine, thymine and uracil bicyclonucleoside monomers, oligomerisation, and unprecedented nucleic acid recognition

Alexei A. Koshkin, Sanjay K. Singh, Poul Nielsen, Vivek K. Rajwanshi, Ravindra Kumar, Michael Meldgaard, Carl Erik Olsen, Jesper Wengel

Tetrahedron · 1998 · 1K citations · 26 references

DOI

Concepts

References

26

PNA hybridizes to complementary oligonucleotides obeying the Watson–Crick hydrogen-bonding rules

Ole Buchardt, Leif Christensen, Carsten Behrens et al. · Nature · 1993 · 2.1K citations

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Conformational analysis of the sugar ring in nucleosides and nucleotides. Improved method for the interpretation of proton magnetic resonance coupling constants

C. Altona, M. Sundaralingam · Journal of the American Chemical Society · 1973 · 797 citations

, , +11

Nucleoside syntheses, XXII<sup>1)</sup> Nucleoside synthesis with trimethylsilyl triflate and perchlorate as catalysts

Helmut Vorbrüggen, Konrad Krolikiewicz, Bärbel Bennua · Chemische Berichte · 1981 · 755 citations

, , +14

The ups and downs of nucleic acid duplex stability: structure-stability studies on chemically-modified DNA:RNA duplexes

Sandra Freier · Nucleic Acids Research · 1997 · 684 citations · Full text

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Synthesis of 2′-O,4′-C-methyleneuridine and -cytidine. Novel bicyclic nucleosides having a fixed C3, -endo sugar puckering

Satoshi Obika, Daishu Nanbu, Yoshiyuki Hari et al. · Tetrahedron Letters · 1997 · 601 citations

, , +13