TDP-43 Depletion in Microglia Promotes Amyloid Clearance but Also Induces Synapse Loss

Clinical diagnosis of Alzheimer's disease

Guy M. McKhann, David A. Drachman, Marshall Folstein et al. · Neurology · 1984 · 28K citations · Full text

Medicine, Geriatric Medicine, Neurology +16

Ubiquitinated TDP-43 in Frontotemporal Lobar Degeneration and Amyotrophic Lateral Sclerosis

Manuela Neumann, Deepak M. Sampathu, Linda K. Kwong et al. · Science · 2006 · 6.6K citations

Life Sciences, Neurology, Neuroscience +14

Resting Microglial Cells Are Highly Dynamic Surveillants of Brain Parenchyma in Vivo

Axel Nimmerjahn, Frank Kirchhoff, Fritjof Helmchen · Science · 2005 · 5.8K citations

Medicine, Neurobiology, Neuroscience +15

Physical basis of cognitive alterations in alzheimer's disease: Synapse loss is the major correlate of cognitive impairment

Robert D. Terry, Eliezer Masliah, David P. Salmon et al. · Annals of Neurology · 1991 · 4.4K citations

Medicine, Neurology, Neuroscience +17

Synaptic Pruning by Microglia Is Necessary for Normal Brain Development

Rosa Chiara Paolicelli, Giulia Bolasco, Francesca Pagani et al. · Science · 2011 · 4.2K citations

Medicine, Neurobiology, Neuroscience +17