Stanley H. Appel

Exome sequencing in amyotrophic lateral sclerosis identifies risk genes and pathways

Elizabeth T. Cirulli, Brittany N. Lasseigne, Slavé Petrovski et al. · Science · 2015 · 972 citations · Full text

Engineering, Exome Sequencing, Genetics +18

Safety and efficacy of eculizumab in anti-acetylcholine receptor antibody-positive refractory generalised myasthenia gravis (REGAIN): a phase 3, randomised, double-blind, placebo-controlled, multicentre study

James F. Howard, Kimiaki Utsugisawa, Michael Benatar et al. · The Lancet Neurology · 2017 · 745 citations

Multicentre Study, Pharmacology, Medicine +3

Wild-type microglia extend survival in PU.1 knockout mice with familial amyotrophic lateral sclerosis

David R. Beers, Jenny S. Henkel, Qin Xiao et al. · Proceedings of the National Academy of Sciences · 2006 · 712 citations · Full text

A unifying hypothesis for the cause of amyotrophic lateral sclerosis, parkinsonism, and alzheimer disease

Stanley H. Appel · Annals of Neurology · 1981 · 697 citations

Natural history of amyotrophic lateral sclerosis in a database population Validation of a scoring system and a model for survival prediction

Lanny J. Haverkamp, Vicki Appel, Stanley H. Appel · Brain · 1995 · 690 citations

Disease Progression, Motor Neuron Disease, Neurological Disorder +17