Edward B. Lee

Stages of pTDP‐43 pathology in amyotrophic lateral sclerosis

Johannes Brettschneider, Kelly Del Tredici, Jon B. Toledo et al. · Annals of Neurology · 2013 · 1K citations · Full text

Large-scale proteomic analysis of Alzheimer’s disease brain and cerebrospinal fluid reveals early changes in energy metabolism associated with microglia and astrocyte activation

Erik C. B. Johnson, Eric B. Dammer, Duc M. Duong et al. · Nature Medicine · 2020 · 993 citations · Full text

Neuroimaging Biomarkers, Neurodegenerative Diseases, Alzheimer's Disease +11

SpaGCN: Integrating gene expression, spatial location and histology to identify spatial domains and spatially variable genes by graph convolutional network

Jian Hu, Xiangjie Li, Kyle Coleman et al. · Nature Methods · 2021 · 981 citations

Functional Genomics, Engineering, Medicine +15

Neurodegenerative disease concomitant proteinopathies are prevalent, age-related and APOE4-associated

John Robinson, Edward B. Lee, Sharon X. Xie et al. · Brain · 2018 · 696 citations · Full text

Corticobasal Degeneration, Social Sciences, Alzheimer's Disease +20

Phosphorylation of S409/410 of TDP-43 is a consistent feature in all sporadic and familial forms of TDP-43 proteinopathies

Manuela Neumann, Linda K. Kwong, Edward B. Lee et al. · Acta Neuropathologica · 2009 · 592 citations · Full text

Signal Transduction, Medicine, Genetics +10