Concepedia

Germline hypomorphic CARD11 mutations in severe atopic disease

Chi A., Jeffrey R. Stinson, Yuan Zhang, Jordan K. Abbott, Michael Weinreich, Pia J. Hauk, Paul R. Reynolds, Jonathan J. Lyons, Celeste Nelson, Elisa Ruffo,

Nature Genetics · 2017 · 218 citations · 37 references

DOI

Concepts

References

37

The kinase mTOR regulates the differentiation of helper T cells through the selective activation of signaling by mTORC1 and mTORC2

Greg M. Delgoffe, Kristen Pollizzi, Adam T. Waickman et al. · Nature Immunology · 2011 · 1.1K citations · Full text

, , +16

Inflammatory T Cell Responses Rely on Amino Acid Transporter ASCT2 Facilitation of Glutamine Uptake and mTORC1 Kinase Activation

Mako Nakaya, Yichuan Xiao, Xiaofei Zhou et al. · Immunity · 2014 · 841 citations · Full text

, , +17

The Association of Atopy with a Gain-of-Function Mutation in the α Subunit of the Interleukin-4 Receptor

Gurjit K. Khurana Hershey, Michal F. Friedrich, Laura A. Esswein et al. · New England Journal of Medicine · 1997 · 746 citations

, , +17

Mammalian Target of Rapamycin Protein Complex 2 Regulates Differentiation of Th1 and Th2 Cell Subsets via Distinct Signaling Pathways

Keunwook Lee, Prathyusha Gudapati, Srdjan M. Dragovic et al. · Immunity · 2010 · 462 citations · Full text

, , +15

Regulatory T Cell Reprogramming toward a Th2-Cell-like Lineage Impairs Oral Tolerance and Promotes Food Allergy

Magali Noval Rivas, Oliver T. Burton, Petra M. Wise et al. · Immunity · 2015 · 360 citations · Full text

, , +15