Jonathan J. Lyons

Loss-of-function mutations in TNFAIP3 leading to A20 haploinsufficiency cause an early-onset autoinflammatory disease

Qing Zhou, Hongying Wang, Daniella M. Schwartz et al. · Nature Genetics · 2015 · 633 citations · Full text

Life Sciences, Genetics, Molecular Genetics +15

Early-onset lymphoproliferation and autoimmunity caused by germline STAT3 gain-of-function mutations

Joshua D. Milner, Tiphanie P. Vogel, Lisa R. Forbes et al. · Blood · 2014 · 556 citations · Full text

Life Sciences, Genetics, Molecular Genetics +14

Elevated basal serum tryptase identifies a multisystem disorder associated with increased TPSAB1 copy number

Jonathan J. Lyons, Xiaomin Yu, Jason D. Hughes et al. · Nature Genetics · 2016 · 393 citations · Full text

Life Sciences, Molecular Genetics, Pathology +8

Autosomal recessive phosphoglucomutase 3 (PGM3) mutations link glycosylation defects to atopy, immune deficiency, autoimmunity, and neurocognitive impairment

Yu Zhang, Xiaomin Yu, Mie Ichikawa et al. · Journal of Allergy and Clinical Immunology · 2014 · 244 citations · Full text

Life Sciences, Genetics, Molecular Genetics +17

Heritable risk for severe anaphylaxis associated with increased α-tryptase–encoding germline copy number at TPSAB1

Jonathan J. Lyons, Jack Chovanec, Michael P. O’Connell et al. · Journal of Allergy and Clinical Immunology · 2020 · 228 citations

Life Sciences, Genetics, Molecular Genetics +17