Jonathan J. Lyons

Loss-of-function mutations in TNFAIP3 leading to A20 haploinsufficiency cause an early-onset autoinflammatory disease

Qing Zhou, Hongying Wang, Daniella M. Schwartz et al. · Nature Genetics · 2015 · 601 citations · Full text

Inflammation, Rheumatology, A20 Haploinsufficiency Cause +14

Early-onset lymphoproliferation and autoimmunity caused by germline STAT3 gain-of-function mutations

Joshua D. Milner, Tiphanie P. Vogel, Lisa R. Forbes et al. · Blood · 2014 · 544 citations · Full text

Elevated basal serum tryptase identifies a multisystem disorder associated with increased TPSAB1 copy number

Jonathan J. Lyons, Xiaomin Yu, Jason D. Hughes et al. · Nature Genetics · 2016 · 376 citations · Full text

Basal Serum Tryptase, Clinical Disorders, Allergy +5

Autosomal recessive phosphoglucomutase 3 (PGM3) mutations link glycosylation defects to atopy, immune deficiency, autoimmunity, and neurocognitive impairment

Yu Zhang, Xiaomin Yu, Mie Ichikawa et al. · Journal of Allergy and Clinical Immunology · 2014 · 238 citations · Full text

Immunogenetics, Immune Deficiency, Autoimmune Disease +14

Heritable risk for severe anaphylaxis associated with increased α-tryptase–encoding germline copy number at TPSAB1

Jonathan J. Lyons, Jack Chovanec, Michael P. O’Connell et al. · Journal of Allergy and Clinical Immunology · 2020 · 213 citations

Allergy, Allergy Medicine, Genetics +11