A novel <scp>GIP</scp> analogue, <scp>ZP</scp> 4165, enhances glucagon‐like peptide‐1‐induced body weight loss and improves glycaemic control in rodents

Abstract

ZP4165 potentiated the anti-obesity effect of a GLP-1 agonist in obese mice and improved glycaemic control in diabetic mice. These studies support further investigation of dual-incretin therapy as a more effective treatment option than mono GLP-1 medication for type 2 diabetes mellitus and obesity.