PLoS ONE · 2013 · 10 citations · 29 references
Life SciencesEndocrinologyMolecular BiologyCell SignalingGene ExpressionSignal TransductionMammalian PhysiologyMuscle DevelopmentMuscle DifferentiationMuscle PhysiologyMuscle StructureMuscle TissueLeptin SignalingMuscle AtrophyMuscle GrowthMyoblast DifferentiationMyoblast ProliferationReceptor IsoformsSkeletal Muscle DifferentiationSkeletal Muscle Physiology
Objective: Leptin receptors are abundant in human skeletal muscle, but the role of leptin in muscle growth, development and aging is not well understood. Here we utilized a novel mouse model lacking all functional leptin receptor isoforms (POUND mouse, Lepr db/lb ) to determine the role of leptin in skeletal muscle.
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A nutrient-sensing pathway regulates leptin gene expression in muscle and fat
Jiali Wang, Rong Liu, Meredith Hawkins et al. · Nature · 1998 · 838 citations
Insulin Signaling in Health and Disease
Morris F. White · Science · 2003 · 725 citations