Concepedia

Publication | Open Access

Hypoxia mediates mitochondrial biogenesis in hepatocellular carcinoma to promote tumor growth through HMGB1 and TLR9 interaction

DOIFull Paper Access

136

Citations

20

References

2017

Year

Samer Tohme, Hamza O. Yazdani, Yao Liu, Patricia Loughran, Dirk J. van der Windt, Hai Huang, Richard L. Simmons, Sruti Shiva, Sheng Tai, Allan Tsung
Hepatology

Abstract

Taken together, our findings suggest that during hypoxia HMGB1 up-regulates mitochondrial biogenesis in HCC cancer cells, promoting tumor survival and proliferation. (Hepatology 2017;66:182-197).

References

YearCitations

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