Christoph Handschin

AMP-activated protein kinase (AMPK) action in skeletal muscle via direct phosphorylation of PGC-1α

Sibylle Jäger, Christoph Handschin, Julie St‐Pierre et al. · Proceedings of the National Academy of Sciences · 2007 · 2.4K citations · Full text

Muscle Function, Direct Phosphorylation, Metabolic Remodeling +21

Suppression of Reactive Oxygen Species and Neurodegeneration by the PGC-1 Transcriptional Coactivators

Julie St‐Pierre, Stavit Drori, Marc Uldry et al. · Cell · 2006 · 2.2K citations · Full text

Reductive Stress, Pgc-1 Transcriptional Coactivators, Developmental Biology +10

PGC-1α protects skeletal muscle from atrophy by suppressing FoxO3 action and atrophy-specific gene transcription

Marco Sandri, Jiandie D. Lin, Christoph Handschin et al. · Proceedings of the National Academy of Sciences · 2006 · 953 citations · Full text

An autoregulatory loop controls peroxisome proliferator-activated receptor γ coactivator 1α expression in muscle

Christoph Handschin, James Rhee, Jiandie D. Lin et al. · Proceedings of the National Academy of Sciences · 2003 · 721 citations · Full text

Errα and Gabpa/b specify PGC-1α-dependent oxidative phosphorylation gene expression that is altered in diabetic muscle

Vamsi K. Mootha, Christoph Handschin, Dan Arlow et al. · Proceedings of the National Academy of Sciences · 2004 · 672 citations · Full text

Insulin Signaling, Metabolic Syndrome, Transcriptional Regulation +20