Inhibition of cloned hERG potassium channels by risperidone and paliperidone

A mechanistic link between an inherited and an acquird cardiac arrthytmia: HERG encodes the IKr potassium channel

Michael C. Sanguinetti, Changan Jiang, Mark Curran et al. · Cell · 1995 · 2.4K citations · Full text

Medicine, Cardiology, Molecular Genetics +16

Class III antiarrhythmic agents have a lot of potential but a long way to go. Reduced effectiveness and dangers of reverse use dependence.

Luc M. Hondeghem, Dirk J. Snyders · Circulation · 1990 · 610 citations · Full text

Medicine, Cardiology, Pharmacology +11

A primate-specific, brain isoform of KCNH2 affects cortical physiology, cognition, neuronal repolarization and risk of schizophrenia

Stephen J. Huffaker, Jingshan Chen, Kristin K. Nicodemus et al. · Nature Medicine · 2009 · 256 citations · Full text

Life Sciences, Neurobiology, Neuroscience +14

Extrapyramidal side effects and tolerability of risperidone: a review.

PubMed · 1994 · 231 citations

Medicine, Pharmacology, Pharmacotherapy +15

Pharmacologic approach to management of agitation associated with dementia.

Mark E. Kunik, Stuart C. Yudofsky, Jonathan Silver et al. · PubMed · 1994 · 203 citations

Medicine, Pharmacology, Pharmacotherapy +17