Concepedia

Ion Channel Modulation

Ion Channel Modulation is the process by which a chemical or physical agent selectively alters the functional state or activity of ion channels, thereby regulating ion flux across cell membranes in a manner distinct from direct pore blockage or permanent structural change.

1.8K

Publications

109K

Citations

7.1K

Authors

1.4K

Institutions

Publications per year

2017–2026

209

Parents

Children

Publications

1.8K

Noxious Cold Ion Channel TRPA1 Is Activated by Pungent Compounds and Bradykinin

Michael Bandell, Gina M. Story, Sun Wook Hwang et al. · Neuron · 2004 · 1.8K citations · Full text

, , +12

Noxious compounds activate TRPA1 ion channels through covalent modification of cysteines

Lindsey J. Macpherson, Adrienne E. Dubin, Michael J. Evans et al. · Nature · 2007 · 1.1K citations · Full text

, , +14

Modulation of A-type potassium channels by a family of calcium sensors

Wei An, Mark R. Bowlby, Maria Betty et al. · Nature · 2000 · 971 citations

, , +14

Protein kinase C reduces Mg2+ block of NMDA-receptor channels as a mechanism of modulation

Li Chen, Li-Yen Mae Huang · Nature · 1992 · 965 citations

, , +14

Vasoregulation by the β1 subunit of the calcium-activated potassium channel

Robert Brenner, Guillermo J. Pérez, Adrian D. Bonev et al. · Nature · 2000 · 802 citations

, , +14

1–5 of 1.8K

Authors

7.1K

  1. FM
    Frances M. Ashcroft

    University of Oxford, United Kingdom

    14 publications · 1.2K citations

    14

    h-index

  2. WA
    William A. Catterall

    University of Washington, United States

    13 publications · 1.7K citations

    12

    h-index

  3. ND
    Nathan Dascal

    Tel Aviv University, Israel

    12 publications · 1.4K citations

    12

    h-index

  4. SO
    Søren‐Peter Olesen

    University of Copenhagen, Denmark

    11 publications · 867 citations

    11

    h-index

  5. FL
    Florian Läng

    University of Tübingen, Germany

    12 publications · 417 citations

    11

    h-index

1–5 of 7.1K

Institutions

1.4K

  1. Centre National de la Recherche Scientifique

    Paris, France

    31 h-index

    46 publications

    2.8K citations

  2. Howard Hughes Medical Institute

    Chevy Chase, United States

    27 h-index

    34 publications

    5.8K citations

  3. Washington University in St. Louis

    St Louis, United States

    24 h-index

    33 publications

    2.6K citations

  4. Yale University

    New Haven, United States

    23 h-index

    24 publications

    1.5K citations

  5. University of Washington

    Seattle, United States

    22 h-index

    27 publications

    3.6K citations

  6. Johns Hopkins University

    Baltimore, United States

    22 h-index

    25 publications

    3.3K citations

  7. Harvard University

    Cambridge, United States

    22 h-index

    23 publications

    2.9K citations

  8. University of Iowa

    Iowa City, United States

    20 h-index

    29 publications

    1.4K citations

1–8 of 1.4K

Venues

  1. Journal of Biological Chemistry

    JBC · 140 publications · 10.3K citations

    66

    h-index

  2. The Journal of General Physiology

    JGP · 104 publications · 7.1K citations

    51

    h-index

  3. Proceedings of the National Academy of Sciences

    PNAS · 68 publications · 6.4K citations

    50

    h-index

  4. The Journal of Physiology

    86 publications · 5.4K citations

    45

    h-index

  5. American Journal of Physiology-Cell Physiology

    63 publications · 2.7K citations

    31

    h-index

1–5