Frances M. Ashcroft

Activating Mutations in the Gene Encoding the ATP-Sensitive Potassium-Channel Subunit Kir6.2 and Permanent Neonatal Diabetes

Anna L. Gloyn, Ewan R. Pearson, Jennifer F. Antcliff et al. · New England Journal of Medicine · 2004 · 1.1K citations

Glucose induces closure of single potassium channels in isolated rat pancreatic β-cells

Frances M. Ashcroft, D E Harrison, Stephen J.H. Ashcroft · Nature · 1984 · 1.1K citations

Molecular Physiology, Signal Transduction, Biochemistry +15

Switching from Insulin to Oral Sulfonylureas in Patients with Diabetes Due to Kir6.2 Mutations

Ewan R. Pearson, Isabelle Flechtner, Pål R. Njølstad et al. · New England Journal of Medicine · 2006 · 979 citations · Full text

Crystal Structure of the Potassium Channel KirBac1.1 in the Closed State

Anling Kuo, Jacqueline M. Gulbis, Jennifer F. Antcliff et al. · Science · 2003 · 784 citations · Full text

Crystal Structure, Molecular Biology, Potassium Channel Kirbac1.1 +17

Truncation of Kir6.2 produces ATP-sensitive K+ channels in the absence of the sulphonylurea receptor

Stephen J. Tucker, Fiona M. Gribble, Chao Zhao et al. · Nature · 1997 · 764 citations

Molecular Pharmacology, Molecular Physiology, Signal Transduction +15