William A. Catterall

The crystal structure of a voltage-gated sodium channel

Jian Payandeh, Todd Scheuer, Ning Zheng et al. · Nature · 2011 · 1.4K citations

Natural Sciences, Biophysics, Crystal Structure +13

Reduced sodium current in GABAergic interneurons in a mouse model of severe myoclonic epilepsy in infancy

Frank H. Yu, Massimo Mantegazza, Ruth E. Westenbroek et al. · Nature Neuroscience · 2006 · 1.2K citations

Medicine, Neurobiology, Neuroscience +17

The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands

Christopher Southan, Joanna L Sharman, Helen E. Benson et al. · Nucleic Acids Research · 2015 · 1K citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

Molecular Determinants of State-Dependent Block of Na ⁺ Channels by Local Anesthetics

David S. Ragsdale, Jancy C. McPhee, Todd Scheuer et al. · Science · 1994 · 861 citations

Medicine, Neuroscience, Pharmacology +17

A cluster of hydrophobic amino acid residues required for fast Na(+)-channel inactivation.

James W. West, D E Patton, Todd Scheuer et al. · Proceedings of the National Academy of Sciences · 1992 · 839 citations

Natural Sciences, Neurobiology, Neuroscience +17