Massimo Mantegazza

Reduced sodium current in GABAergic interneurons in a mouse model of severe myoclonic epilepsy in infancy

Frank H. Yu, Massimo Mantegazza, Ruth E. Westenbroek et al. · Nature Neuroscience · 2006 · 1.2K citations

Medicine, Neurobiology, Neuroscience +17

Identification of an Na _v 1.1 sodium channel (SCN1A) loss-of-function mutation associated with familial simple febrile seizures

Massimo Mantegazza, Antonio Gambardella, Raffaella Rusconi et al. · Proceedings of the National Academy of Sciences · 2005 · 195 citations · Full text

Life Sciences, Genetics, Neurology +17

Inhibition of Transient and Persistent Na+ Current Fractions by the New Anticonvulsant Topiramate

Stefano Taverna, Giulio Sancini, Massimo Mantegazza et al. · Journal of Pharmacology and Experimental Therapeutics · 1999 · 183 citations

Life Sciences, Neuroscience, Pharmacology +17

Impaired Action Potential Initiation in GABAergic Interneurons Causes Hyperexcitable Networks in an Epileptic Mouse Model Carrying a Human Na_V1.1 Mutation

Ulrike B. S. Hedrich, Camille Liautard, Daniel S. Kirschenbaum et al. · Journal of Neuroscience · 2014 · 164 citations · Full text

Life Sciences, Neurobiology, Neuroscience +17

The gain of function <i>SCN1A</i> disorder spectrum: novel epilepsy phenotypes and therapeutic implications

Andreas Brunklaus, Tobias Brünger, Tony Feng et al. · Brain · 2022 · 156 citations · Full text

Medicine, Genetics, Neurology +17