A mechanistic link between an inherited and an acquird cardiac arrthytmia: HERG encodes the IKr potassium channel

Michael C. Sanguinetti, Changan Jiang, Mark Curran, +1

Cell

Cardiac MuscleCardiomyopathyMolecular PhysiologyAcquird Cardiac ArrthytmiaPhysiology +8

A molecular basis for cardiac arrhythmia: HERG mutations cause long QT syndrome

Mark Curran, Igor Splawski, Katherine W. Timothy, +3

Cell

Long Qt SyndromeCardiomyopathyGeneticsCardiac ArrhythmiaHerg Mutations +7

Coassembly of KVLQT1 and minK (IsK) proteins to form cardiac IKS potassium channel

Michael C. Sanguinetti, Mark Curran, Anruo Zou, +4

Nature

Cardiac MuscleChannelopathiesCardiomyopathySignal TransductionMolecular Physiology +9

Positional cloning of a novel potassium channel gene: KVLQT1 mutations cause cardiac arrhythmias

Q. Wang, Mark Curran, Igor Splawski, +13

Nature Genetics

Cardiac MuscleChannelopathiesKvlqt1 MutationsMolecular PhysiologyGenetics +7

Spectrum of HERG K+-channel dysfunction in an inherited cardiac arrhythmia.

Michael C. Sanguinetti, Mark Curran, Peter Spector, +1

Proceedings of the National Academy of Sciences

Cardiac MuscleGeneticsSudden DeathMolecular GeneticsCongenital Heart Anomaly +18

Fast inactivation causes rectification of the IKr channel.

Peter Spector, Mark Curran, Anruo Zou, +2

The Journal of General Physiology

Cardiac MuscleTruncated ChannelCellular PhysiologySocial SciencesHerg Rectification +15

Idiopathic congenital central hypoventilation syndrome: Analysis of genes pertinent to early autonomic nervous system embryologic development and identification of mutations in PHOX2b

Debra E. Weese‐Mayer, Elizabeth Berry‐Kravis, Lili Zhou, +4

American Journal of Medical Genetics Part A

A Genomewide Analysis Provides Evidence for Novel Linkages in Inflammatory Bowel Disease in a Large European Cohort

Jochen Hampe, Stefan Schreiber, Sarah H. Shaw, +16

The American Journal of Human Genetics

Genome-wide Association StudyChronic Inflammatory DiseasesMolecular EpidemiologyNovel LinkagesMedicine +9

Ethnic Differences in Cardiac Potassium Channel Variants: Implications for Genetic Susceptibility to Sudden Cardiac Death and Genetic Testing for Congenital Long QT Syndrome

Michael J. Ackerman, David J. Tester, Gregg S. Jones, +3

Mayo Clinic Proceedings

CardiomyopathyGenetic TestingCardiovascular DiseaseGeneticsPhysiology +10

Spectrum and prevalence of cardiac sodium channel variants among black, white, Asian, and Hispanic individuals: Implications for arrhythmogenic susceptibility and Brugada/long QT syndrome genetic testing

Michael J. Ackerman, Igor Splawski, Jonathan C. Makielski, +11

Heart Rhythm

CardiomyopathyGenetic TestingEpidemiologyCardiovascular DiseaseGenetics +8