Effect of the Anti-C1s Humanized Antibody TNT009 and Its Parental Mouse Variant TNT003 on HLA Antibody–Induced Complement Activation—A Preclinical In Vitro Study

Complement-Binding Anti-HLA Antibodies and Kidney-Allograft Survival

Alexandre Loupy, Carmen Lefaucheur, Déwi Vernerey et al. · New England Journal of Medicine · 2013 · 833 citations · Full text

Life Sciences, Immunology, Surgery +17

Terminal Complement Inhibition Decreases Antibody-Mediated Rejection in Sensitized Renal Transplant Recipients

Mark D. Stegall, Tayyab S. Diwan, Suresh Raghavaiah et al. · American Journal of Transplantation · 2011 · 570 citations

Life Sciences, Immunology, Nephrology +16

Activation of cultured human endothelial cells by recombinant lymphotoxin: comparison with tumor necrosis factor and interleukin 1 species.

Jordan S. Pober, Lynne A. Lapierre, Alan H. Stolpen et al. · The Journal of Immunology · 1987 · 421 citations · Full text

Life Sciences, Cell Biology, Immunology +17

The Use of Antibody to Complement Protein C5 for Salvage Treatment of Severe Antibody-Mediated Rejection

Jayme E. Locke, Cynthia M. Magro, A.L. Singer et al. · American Journal of Transplantation · 2008 · 320 citations · Full text

Life Sciences, Hematology, Immunology +17

Human monoclonal IgG isotypes differ in complement activating function at the level of C4 as well as C1q.

C Bindon, G Hale, M. Brüggemann et al. · The Journal of Experimental Medicine · 1988 · 296 citations · Full text

Life Sciences, Cell Biology, Immunology +14