Concepedia

Blocking celiac antigenicity of the glutamine-rich gliadin 33-mer peptide by microbial transglutaminase

Lin Zhou, Yujie Wu, Youfei Cheng, Jie Wang, Jun Lü, Jinyan Gao, Juanli Yuan

RSC Advances · 2017 · 13 citations · 27 references

DOIFull text

Open access

Concepts

Abstract

Transamidation by mTG with variety of acyl-acceptor substrates decreased the antigenicity of gliadin peptide related to celiac disease.

References

27

The Oslo definitions for coeliac disease and related terms

Jonas F. Ludvigsson, Daniel A. Leffler, Julio C. Bai et al. · Gut · 2012 · 1.7K citations · Full text

, , +17

Structural Basis for Gluten Intolerance in Celiac Sprue

Lu Shan, Øyvind Molberg, Isabelle Parrot et al. · Science · 2002 · 1.6K citations

, , +17

Tissue transglutaminase selectively modifies gliadin peptides that are recognized by gut-derived T cells in celiac disease

Øyvind Molberg, Stephen N. McAdam, Roman Körner et al. · Nature Medicine · 1998 · 1.2K citations

, , +13

Selective deamidation by tissue transglutaminase strongly enhances gliadin-specific T cell reactivity.

Y. van de Wal, Y Kooy, Peter A. van Veelen et al. · PubMed · 1998 · 491 citations

, , +17

Cutting Edge: Selective Deamidation by Tissue Transglutaminase Strongly Enhances Gliadin-Specific T Cell Reactivity

Yvonne van de Wal, Y Kooy, Peter A. van Veelen et al. · The Journal of Immunology · 1998 · 431 citations · Full text

, , +17