Concepedia

Synthesis and biological evaluation of potential inhibitors of the cysteine proteases cruzain and rhodesain designed by molecular simplification

Saulo Fehelberg Pinto Braga, Luan Carvalho Martins, Elany Barbosa da Silva, Policarpo Ademar Sales, Silvane Maria Fonseca Murta, Álvaro J. Romanha, Wai Tuck Soh, Hans Brandstetter, Rafaela Salgado Ferreira, Renata Barbosa de Oliveira

Bioorganic & Medicinal Chemistry · 2017 · 50 citations · 36 references

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36

Molecular Properties That Influence the Oral Bioavailability of Drug Candidates

Daniel F. Veber, Stephen R. Johnson, Hung‐Yuan Cheng et al. · Journal of Medicinal Chemistry · 2002 · 8.1K citations

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Randomized Trial of Benznidazole for Chronic Chagas’ Cardiomyopathy

Carlos A. Morillo, José Antônio Marin‐Neto, Álvaro Avezum et al. · New England Journal of Medicine · 2015 · 1K citations · Full text

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Global economic burden of Chagas disease: a computational simulation model

Bruce Y. Lee, Kristina M. Bacon, María Elena Bottazzi et al. · The Lancet Infectious Diseases · 2013 · 634 citations

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Efficient technique for screening drugs for activity against Trypanosoma cruzi using parasites expressing beta-galactosidase

Frederick S. Buckner, Christophe L. M. J. Verlinde, Anne Camille La Flamme et al. · Antimicrobial Agents and Chemotherapy · 1996 · 540 citations · Full text

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In vitro and in vivo experimental models for drug screening and development for Chagas disease

Álvaro J. Romanha, Solange L. de Castro, Maria de Nazaré Correia Soeiro et al. · Memórias do Instituto Oswaldo Cruz · 2010 · 349 citations · Full text

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