Elany Barbosa da Silva

AI is a viable alternative to high throughput screening: a 318-target study

Izhar Wallach, Denzil Bernard, Kong T. Nguyen et al. · Scientific Reports · 2024 · 120 citations · Full text

Pharmacy, Bioinformatics, Medicinal Chemistry +16

2-Pyridyl thiazoles as novel anti-Trypanosoma cruzi agents: Structural design, synthesis and pharmacological evaluation

Marcos Veríssimo de Oliveira Cardoso, Lucianna Râbelo Pessôa de Siqueira, Elany Barbosa da Silva et al. · European Journal of Medicinal Chemistry · 2014 · 102 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +15

Small-Molecule Thioesters as SARS-CoV-2 Main Protease Inhibitors: Enzyme Inhibition, Structure–Activity Relationships, Antiviral Activity, and X-ray Structure Determination

Thanigaimalai Pillaiyar, Philipp Flury, Nadine Krüger et al. · Journal of Medicinal Chemistry · 2022 · 67 citations · Full text

Life Sciences, Medicinal Chemistry, Pharmacology +16

Antitumor and immunomodulatory activities of thiosemicarbazones and 1,3-Thiazoles in Jurkat and HT-29 cells

Thiago André Ramos dos Santos, Aline Caroline da Silva, Elany Barbosa da Silva et al. · Biomedicine & Pharmacotherapy · 2016 · 62 citations · Full text

Life Sciences, Immunology, Pharmacology +10

Computer-aided design of 1,4-naphthoquinone-based inhibitors targeting cruzain and rhodesain cysteine proteases

Leandro Rocha Silva, Ari Souza Guimarães, Jadiely do Nascimento et al. · Bioorganic & Medicinal Chemistry · 2021 · 57 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +13