Phenethyl isothiocyanate suppresses cancer stem cell properties in vitro and in a xenograft model

An embryonic stem cell–like gene expression signature in poorly differentiated aggressive human tumors

Ittai Ben‐Porath, Matthew Thomson, Vincent J. Carey et al. · Nature Genetics · 2008 · 2.6K citations · Full text

Life Sciences, Cancer Biology, Oncology +16

The role of PTEN/Akt/PI3K signaling in the maintenance and viability of prostate cancer stem-like cell populations

Anna Dubrovska, Sungeun Kim, Richard J. Salamone et al. · Proceedings of the National Academy of Sciences · 2008 · 563 citations · Full text

Medicine, Cell Biology, Oncology +17

Octamer 4 (Oct4) mediates chemotherapeutic drug resistance in liver cancer cells through a potential Oct4–AKT–ATP‐binding cassette G2 pathway†

Xiao Qi Wang, Weg M. Ongkeko, Lin Chen et al. · Hepatology · 2010 · 236 citations · Full text

Medicine, Oncology, Pharmacology +17

Synergistic Activity of Sorafenib and Sulforaphane Abolishes Pancreatic Cancer Stem Cell Characteristics

Vanessa Rausch, Li Liu, Georgios Kallifatidis et al. · Cancer Research · 2010 · 209 citations

Medicine, Oncology, Pharmacology +17

Epithelial cell adhesion molecule (EpCAM) is associated with prostate cancer metastasis and chemo/radioresistance via the PI3K/Akt/mTOR signaling pathway

Jie Ni, Paul Cozzi, Jingli Hao et al. · The International Journal of Biochemistry & Cell Biology · 2013 · 202 citations

Medicine, Molecular Biology, Oncology +14