PI3K/Akt/mTOR pathway inhibitors enhance radiosensitivity in radioresistant prostate cancer cells through inducing apoptosis, reducing autophagy, suppressing NHEJ and HR repair pathways

Lei Chang, Peter Graham, Jingli Hao, +5

Cell Death and Disease

Epithelial cell adhesion molecule (EpCAM) is associated with prostate cancer metastasis and chemo/radioresistance via the PI3K/Akt/mTOR signaling pathway

Jie Ni, Paul Cozzi, Jingli Hao, +9

The International Journal of Biochemistry & Cell Biology

UrologyPerineural InvasionMedicineProstatic DiseaseMatrix Biology +5

Co-expression of CD147/EMMPRIN with monocarboxylate transporters and multiple drug resistance proteins is associated with epithelial ovarian cancer progression

Hongmin Chen, Li Wang, Julia Beretov, +3

Clinical & Experimental Metastasis

MedicinePharmacologyMonocarboxylate TransportersTumor SuppressorCancer Treatment +6

In Vitro and In Vivo Prostate Cancer Metastasis and Chemoresistance Can Be Modulated by Expression of either CD44 or CD147

Jingli Hao, Michele C. Madigan, Aparajita Khatri, +9

PLoS ONE

Tumor BiologyGenitourinary CancerMedicineCap CellsCancer Cell Biology +9

Identification of protein biomarkers and signaling pathways associated with prostate cancer radioresistance using label-free LC-MS/MS proteomic approach

Lei Chang, Jie Ni, Julia Beretov, +7

Scientific Reports

Cancer Stem Cells in Prostate Cancer Chemoresistance

Jie Ni, Paul Cozzi, Jingli Hao, +4

Current Cancer Drug Targets

Adult Stem CellStem Cell BiologyCancer BiologyTumor BiologyCancer Cell Biology +14

Combination Therapy with the Histone Deacetylase Inhibitor LBH589 and Radiation Is an Effective Regimen for Prostate Cancer Cells

Weiwei Xiao, Peter Graham, Jingli Hao, +6

PLoS ONE

Prostate Cancer CellsCancer BiologyTumor BiologyRadiation MedicineOncology +14

CD44 is a biomarker associated with human prostate cancer radiation sensitivity

Weiwei Xiao, Peter Graham, Carl Power, +3

Clinical & Experimental Metastasis

OncologyGenitourinary CancerMedicinePathologyCancer Genomics +6

Monoclonal antibody targeting MUC1 and increasing sensitivity to docetaxel as a novel strategy in treating human epithelial ovarian cancer

Li Wang, Hongmin Chen, Fenghua Liu, +8

Cancer Letters

OncologyNovel StrategyMedicineGynecologyTumor Targeting +6

Proteomic identification of the lactate dehydrogenase A in a radioresistant prostate cancer xenograft mouse model for improving radiotherapy

Jingli Hao, Peter Graham, Lei Chang, +9

Oncotarget

Tumor BiologyRadiation MedicineOncologyEndocrine-related CancerBiochemistry +13