Investigating the inhibitory effects of zinc ions on amyloid fibril formation of hen egg-white lysozyme

α-Synuclein strains cause distinct synucleinopathies after local and systemic administration

Wouter Peelaerts, Luc Bousset, Anke Van der Perren et al. · Nature · 2015 · 1.1K citations · Full text

Life Sciences, Neurology, Neuroscience +13

Metal-triggered Structural Transformations, Aggregation, and Fibrillation of Human α-Synuclein

Vladimir N. Uversky, Jie Li, Anthony L. Fink · Journal of Biological Chemistry · 2001 · 1.1K citations · Full text

Life Sciences, Neurology, Neuroscience +16

Systematic analysis of nucleation-dependent polymerization reveals new insights into the mechanism of amyloid self-assembly

Wei‐Feng Xue, Steve W. Homans, Sheena E. Radford · Proceedings of the National Academy of Sciences · 2008 · 486 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +17

Trace amounts of copper in water induce β-amyloid plaques and learning deficits in a rabbit model of Alzheimer's disease

David L. Sparks, Bernard G. Schreurs · Proceedings of the National Academy of Sciences · 2003 · 453 citations · Full text

Life Sciences, Neurobiology, Neuroscience +17

Structural characterization of copper(II) binding to α-synuclein: Insights into the bioinorganic chemistry of Parkinson's disease

Rodolfo M. Rasia, Carlos W. Bertoncini, Derek Marsh et al. · Proceedings of the National Academy of Sciences · 2005 · 405 citations · Full text

Life Sciences, Biochemistry, Chemistry +17