Concepedia

Hypoxia-Inducible Factors and Cancer

Jonathan C. Jun, Aman Rathore, Haris Younas, Daniele M. Gilkes, Vsevolod Y. Polotsky

Current Sleep Medicine Reports · 2017 · 249 citations · 111 references

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References

111

Hypoxia-inducible factor 1 is a basic-helix-loop-helix-PAS heterodimer regulated by cellular O2 tension.

G L Wang, Bing‐Hua Jiang, E A Rue et al. · Proceedings of the National Academy of Sciences · 1995 · 6.2K citations

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The tumour suppressor protein VHL targets hypoxia-inducible factors for oxygen-dependent proteolysis

Patrick H. Maxwell, Michael S. Wiesener, Gin-Wen Chang et al. · Nature · 1999 · 5.2K citations

, , +14

THE METABOLISM OF TUMORS IN THE BODY

Otto Warbürg, Franz Wind, Erwin Negelein · The Journal of General Physiology · 1927 · 4.4K citations · Full text

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HIF-1-mediated expression of pyruvate dehydrogenase kinase: A metabolic switch required for cellular adaptation to hypoxia

Jung‐whan Kim, Irina Tchernyshyov, Gregg L. Semenza et al. · Cell Metabolism · 2006 · 3.9K citations · Full text

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Identification of the von Hippel-Lindau Disease Tumor Suppressor Gene

Farida Latif, Kálmán Tory, James R. Gnarra et al. · Science · 1993 · 3K citations

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