Concepedia

Pleurotus giganteus (Berk. Karun & Hyde), the giant oyster mushroom inhibits NO production in LPS/H2O2 stimulated RAW 264.7 cells via STAT 3 and COX-2 pathways

Asweni Baskaran, Kek Heng Chua, Vikineswary Sabaratnam, Mani Ravishankar Ram, Umah Rani Kuppusamy

BMC Complementary and Alternative Medicine · 2017 · 25 citations · 22 references

DOIFull text

Open access

Abstract

Our data suggest that the anti-inflammatory activity of EPG is mediated via the suppression of the STAT 3 and COX-2 pathways and can serve as potential endogenous antioxidant stimulant.

References

22

C-Reactive Protein and Other Markers of Inflammation in the Prediction of Cardiovascular Disease in Women

Paul M. Ridker, Charles H. Hennekens, Julie E. Buring et al. · New England Journal of Medicine · 2000 · 5.8K citations · Full text

Pharmacological and biochemical demonstration of the role of cyclooxygenase 2 in inflammation and pain.

Karen Seibert, Y Zhang, K. Leahy et al. · Proceedings of the National Academy of Sciences · 1994 · 1.6K citations · Full text

, , +22

Oxidants, antioxidants and carcinogenesis.

Gibanananda Ray, Syed Akhtar Husain · PubMed · 2002 · 346 citations

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Anti-inflammatory activity of methanolic extracts from edible mushrooms in LPS activated RAW 264.7 macrophages

Carlos Moro, Irene Palacios, Miguel Lozano et al. · Food Chemistry · 2011 · 204 citations

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Suppression of the inflammatory response by triterpenes isolated from the mushroom Ganoderma lucidum

Shailesh Dudhgaonkar, Anita Thyagarajan, Daniel Slíva · International Immunopharmacology · 2009 · 184 citations

, , +7