Concepedia

Halofuginone enhances the chemo-sensitivity of cancer cells by suppressing NRF2 accumulation

Kouhei Tsuchida, Tadayuki Tsujita, Makiko Hayashi, Asaka Ojima, Nadine Keleku-Lukwete, Fumiki Katsuoka, Akihito Otsuki, Haruhisa Kikuchi, Yoshiteru Oshima, Mikiko Suzuki,

Free Radical Biology and Medicine · 2016 · 166 citations · 54 references

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References

54

Mutational landscape and significance across 12 major cancer types

Cyriac Kandoth, Michael D. McLellan, Fabio Vandin et al. · Nature · 2013 · 4.5K citations · Full text

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An Nrf2/Small Maf Heterodimer Mediates the Induction of Phase II Detoxifying Enzyme Genes through Antioxidant Response Elements

Ken Itoh, Tomoki Chiba, Satoru Takahashi et al. · Biochemical and Biophysical Research Communications · 1997 · 4K citations

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Keap1 represses nuclear activation of antioxidant responsive elements by Nrf2 through binding to the amino-terminal Neh2 domain

Ken Itoh, Nobunao Wakabayashi, Yasutake Katoh et al. · Genes & Development · 1999 · 3.6K citations · Full text

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An Integrated Stress Response Regulates Amino Acid Metabolism and Resistance to Oxidative Stress

Heather P. Harding, Yuhong Zhang, Huiquing Zeng et al. · Molecular Cell · 2003 · 3.3K citations · Full text

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Regulated Translation Initiation Controls Stress-Induced Gene Expression in Mammalian Cells

Heather P. Harding, Isabel Novoa, Yuhong Zhang et al. · Molecular Cell · 2000 · 3.2K citations · Full text

, , +12