Haruhisa Kikuchi

Halofuginone enhances the chemo-sensitivity of cancer cells by suppressing NRF2 accumulation

Kouhei Tsuchida, Tadayuki Tsujita, Makiko Hayashi et al. · Free Radical Biology and Medicine · 2016 · 163 citations

Nrf2 Accumulation, Chemoprevention Strategy, Medicine +10

Exploration of a New Type of Antimalarial Compounds Based on Febrifugine

Haruhisa Kikuchi, Keisuke Yamamoto, Seiko Horoiwa et al. · Journal of Medicinal Chemistry · 2006 · 147 citations

Medicinal Chemistry, Antiviral Compound, Biochemistry +14

MalariaCount: An image analysis-based program for the accurate determination of parasitemia

Selena W. S. Sio, Weiling Sun, Saravana Kumar et al. · Journal of Microbiological Methods · 2006 · 130 citations

Parasitic Disease, Accurate Determination, Image Analysis-based Program +11

Structure of Prolyl-tRNA Synthetase-Halofuginone Complex Provides Basis for Development of Drugs against Malaria and Toxoplasmosis

Vitul Jain, M. Yogavel, Yoshiteru Oshima et al. · Structure · 2015 · 118 citations · Full text

Biosynthesis, Biochemistry, Antiparasitic Agent +7

A newly established in vitro culture using transgenic Drosophila reveals functional coupling between the phospholipase A2-generated fatty acid cascade and lipopolysaccharide-dependent activation of the immune deficiency (imd) pathway in insect immunity

Masashi Yajima, Masatoshi Takada, N. Takahashi et al. · Biochemical Journal · 2003 · 105 citations · Full text