Concepedia

XRCC1 mutation is associated with PARP1 hyperactivation and cerebellar ataxia

Nícolas C. Hoch, Hana Hanzlíková, Stuart L. Rulten, Martine Tétreault, Emilia Komulainen, Limei Ju, P. Hornyak, Zhihong Zeng, William H. Gittens, Stéphanie Rey,

Nature · 2016 · 271 citations · 22 references

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22

RNA-Guided Human Genome Engineering via Cas9

Prashant Mali, Luhan Yang, Kevin M. Esvelt et al. · Science · 2013 · 9.4K citations · Full text

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Improving CRISPR-Cas nuclease specificity using truncated guide RNAs

Yanfang Fu, Jeffry D. Sander, Deepak Reyon et al. · Nature Biotechnology · 2014 · 2K citations · Full text

, , +14

Poly(ADP-ribose) polymerase gene disruption renders mice resistant to cerebral ischemia

Mikael J. L. Eliasson, Kenji Sampei, Allen S. Mandir et al. · Nature Medicine · 1997 · 1K citations

, , +14

Mice lacking ADPRT and poly(ADP-ribosyl)ation develop normally but are susceptible to skin disease.

Z Q Wang, B. Auer, Laura Stingl et al. · Genes & Development · 1995 · 779 citations · Full text

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X-ray induced DNA double strand break production and repair in mammalian cells as measured by neutral filter elution

Matthews O. Bradley, Kurt W. Kohn · Nucleic Acids Research · 1979 · 572 citations · Full text

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