Hana Hanzlíková

The Importance of Poly(ADP-Ribose) Polymerase as a Sensor of Unligated Okazaki Fragments during DNA Replication

Hana Hanzlíková, Ilona Kalasová, Annie Albert Demin et al. · Molecular Cell · 2018 · 390 citations · Full text

Chromatin, Genome Instability, Biochemistry +13

XRCC1 mutation is associated with PARP1 hyperactivation and cerebellar ataxia

Nícolas C. Hoch, Hana Hanzlíková, Stuart L. Rulten et al. · Nature · 2016 · 263 citations · Full text

Xrcc1 Mutation, Molecular Neuroscience, Genetic Disorder +6

Neuronal enhancers are hotspots for DNA single-strand break repair

Wei Wu, Sarah E. Hill, William J. Nathan et al. · Nature · 2021 · 223 citations · Full text

Neuronal Enhancers, Chromatin, Genome Instability +7

Overlapping roles for PARP1 and PARP2 in the recruitment of endogenous XRCC1 and PNKP into oxidized chromatin

Hana Hanzlíková, William H. Gittens, Kateřina Krejčíková et al. · Nucleic Acids Research · 2016 · 198 citations · Full text

Endogenous Xrcc1, Chromatin, Genome Instability +14

XRCC1 prevents toxic PARP1 trapping during DNA base excision repair

Annie Albert Demin, Kouji Hirota, Masataka Tsuda et al. · Molecular Cell · 2021 · 188 citations · Full text